Guidelines Articles

Approaches for bridging therapy prior to chimeric antigen receptor T cells for relapsed/refractory acute lymphoblastic B-lineage leukemia in children and young adults (1035 Online Views)

Tobias Feuchtinger, Peter Bader, Marion Subklewe, Maike Breidenbach, Semjon Willier, Markus Metzler, Nicola Gökbuget, Julia Hauer, Fabian Müller, Paul-Gerhardt Schlegel, Michael Frühwald, Christoph Schmid, Anja Troeger, Claudia Baldus, Roland Meisel, Annette Künkele, Max Topp, Jean-Pierre Bourquin, Gunnar Cario, Arend von Stackelberg, Christina Peters


Towards personalized prevention of Herpes zoster infection in patients with hematologic diseases or hematopoietic stem cell transplant recipients: a position paper from an ad hoc Italian expert panel (1948 Online Views)

Corrado Girmenia, Fabio Ciceri, Paolo Corradini, Antonio Cuneo, Fortunato D’Ancona, Pellegrino Musto, Antonio Maria Risitano, Maria Teresa Voso, Adriano Venditti, Giovanni Barosi


Thrombosis in multiple myeloma: risk stratification, antithrombotic prophylaxis, and management of acute events. A consensus-based position paper from an ad hoc expert panel (5354 Online Views)

Valerio De Stefano, Alessandra Larocca, Monica Carpenedo, Michele Cavo, Francesco Di Raimondo, Anna Falanga, Massimo Offidani, Maria Teresa Petrucci, Marco Ruggeri, Roberto Mario Santi, Giovanni Barosi


Kreuth V initiative: European consensus proposals for treatment of hemophilia using standard products, extended half-life coagulation factor concentrates and non-replacement therapies (3230 Online Views)

Flora Peyvandi, Karin Berger, Rainer Seitz, Anneliese Hilger, Marie-Laure Hecquet, Michael Wierer, Karl-Heinz Buchheit, Brian O’Mahony, Amanda Bok, Mike Makris, Ulrich Mansmann, Wolfgang Schramm, Pier Mannuccio Mannucci


International recommendations on the diagnosis and treatment of acquired hemophilia A (55565 Online Views)

Andreas Tiede, Peter Collins, Paul Knoebl, Jerome Teitel, Craig Kessler, Midori Shima, Giovanni Di Minno, Roseline d’Oiron, Peter Salaj, Victor Jiménez-Yuste, Angela Huth-Kühne, Paul Giangrande


Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3-internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (11360 Online Views)

Ali Bazarbachi, Gesine Bug, Frederic Baron, Eolia Brissot, Fabio Ciceri, Iman Abou Dalle, Hartmut Döhner, Jordi Esteve, Yngvar Floisand, Sebastian Giebel, Maria Gilleece, Norbert-Claude Gorin, Elias Jabbour, Mahmoud Aljurf, Hagop Kantarjian, Mohamed Kharfan-Dabaja, Myriam Labopin, Francesco Lanza, Florent Malard, Zinaida Peric, Thomas Prebet, Farhad Ravandi, Annalisa Ruggeri, Jaime Sanz, Christoph Schmid, Roni Shouval, Alexandros Spyridonidis, Jurjen Versluis, Norbert Vey, Bipin N Savani, Arnon Nagler, Mohamad Mohty


Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) (29148 Online Views)

Ibrahim Yakoub-Agha, Christian Chabannon, Peter Bader, Grzegorz W. Basak, Halvard Bonig, Fabio Ciceri, Selim Corbacioglu, Rafael F. Duarte, Hermann Einsele, Michael Hudecek, Marie José Kersten, Ulrike Köhl, Jürgen Kuball, Stephan Mielke, Mohamad Mohty, John Murray, Arnon Nagler, Stephen Robinson, Riccardo Saccardi, Fermin Sanchez-Guijo, John A. Snowden, Micha Srour, Jan Styczynski, Alvaro Urbano-Ispizua, Patrick J. Hayden, Nicolaus Kröger


Clinical applications of donor lymphocyte infusion from an HLA-haploidentical donor: consensus recommendations from the Acute Leukemia Working Party of the EBMT (10711 Online Views)

Bhagirathbhai Dholaria, Bipin N. Savani, Myriam Labopin, Leo Luznik, Annalisa Ruggeri, Stephan Mielke, Monzr M. Al Malki, Piyanuch Kongtim, Ephraim Fuchs, Xiao-Jun Huang, Franco Locatelli, Franco Aversa, Luca Castagna, Andrea Bacigalupo, Massimo Martelli, Didier Blaise, Patrick Ben Soussan, Yolande Arnault, Rupert Handgretinger, Denis-Claude Roy, Paul O’Donnell, Asad Bashey, Scott Solomon, Rizwan Romee, Philippe Lewalle, Jorge Gayoso, Michael Maschan, Hillard M. Lazarus, Karen Ballen, Sebastian Giebel, Frederic Baron, Fabio Ciceri, Jordi Esteve, Norbert-Claude Gorin, Alexandros Spyridonidis, Christoph Schmid, Stefan O. Ciurea, Arnon Nagler, Mohamad Mohty


Chimeric antigen receptor T-cell therapy for multiple myeloma: a consensus statement from The European Myeloma Network (7029 Online Views)

Philippe Moreau, Pieter Sonneveld, Mario Boccadoro, Gordon Cook, Ma Victoria Mateos, Hareth Nahi, Hartmut Goldschmidt, Meletios A. Dimopoulos, Paulo Lucio, Joan Bladé, Michel Delforge, Roman Hajek, Heinz Ludwig, Thierry Facon, Jesus F. San Miguel, Hermann Einsele


Guidelines from the 2017 European Conference on Infections in Leukaemia for management of HHV-6 infection in patients with hematologic malignancies and after hematopoietic stem cell transplantation (19259 Online Views)

Katherine N Ward, Joshua A Hill, Petr Hubacek, Rafael de la Camara, Roberto Crocchiolo, Hermann Einsele, David Navarro, Christine Robin, Catherine Cordonnier, Per Ljungman


Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions (15555 Online Views)

Peter Valent, Attilio Orazi, Michael R. Savona, Mrinal M. Patnaik, Francesco Onida, Arjan A. van de Loosdrecht, Detlef Haase, Torsten Haferlach, Chiara Elena, Lisa Pleyer, Wolfgang Kern, Tea Pemovska, Gregory I. Vladimer, Julie Schanz, Alexandra Keller, Michael Lübbert, Thomas Lion, Karl Sotlar, Andreas Reiter, Theo De Witte, Michael Pfeilstöcker, Klaus Geissler, Eric Padron, Michael Deininger, Alberto Orfao, Hans-Peter Horny, Peter L. Greenberg, Daniel A. Arber, Luca Malcovati, John M. Bennett


European Myeloma Network recommendations on tools for the diagnosis and monitoring of multiple myeloma: what to use and when (12983 Online Views)

Jo Caers, Laurent Garderet, K. Martin Kortüm, Michael E. O’Dwyer, Niels W.C.J. van de Donk, Mascha Binder, Sandra Maria Dold, Francesca Gay, Jill Corre, Yves Beguin, Heinz Ludwig, Alessandra Larocca, Christoph Driessen, Meletios A. Dimopoulos, Mario Boccadoro, Martin Gramatzki, Sonja Zweegman, Hermann Einsele, Michele Cavo, Hartmut Goldschmidt, Pieter Sonneveld, Michel Delforge, Holger W. Auner, Evangelos Terpos, Monika Engelhardt


Haploidentical hematopoietic cell transplantation for adult acute myeloid leukemia: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (6586 Online Views)

Catherine J Lee, Bipin N Savani, Mohamad Mohty, Myriam Labopin, Annalisa Ruggeri, Christoph Schmid, Frédéric Baron, Jordi Esteve, Norbert C Gorin, Sebastian Giebel, Fabio Ciceri, Arnon Nagler


Recommendations regarding splenectomy in hereditary hemolytic anemias (11780 Online Views)

Achille Iolascon, Immacolata Andolfo, Wilma Barcellini, Francesco Corcione, Loïc Garçon, Lucia De Franceschi, Claudio Pignata, Giovanna Graziadei, Dagmar Pospisilova, David C. Rees, Mariane de Montalembert, Stefano Rivella, Antonella Gambale, Roberta Russo, Leticia Ribeiro, Jules Vives-Corrons, Patricia Aguilar Martinez, Antonis Kattamis, Beatrice Gulbis, Maria Domenica Cappellini, Irene Roberts, Hannah Tamary


Risk factors for mortality in adult patients with sickle cell disease: a meta-analysis of studies in North America and Europe (5308 Online Views)

Poulami Maitra, Melissa Caughey, Laura Robinson, Payal C. Desai, Susan Jones, Mehdi Nouraie, Mark T. Gladwin, Alan Hinderliter, Jianwen Cai, Kenneth I. Ataga


ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients (34071 Online Views)

Frederic Tissot, Samir Agrawal, Livio Pagano, Georgios Petrikkos, Andreas H. Groll, Anna Skiada, Cornelia Lass-Flörl, Thierry Calandra, Claudio Viscoli, Raoul Herbrecht


Guidelines for diagnosis, prevention and management of central nervous system involvement in diffuse large B-cell lymphoma patients by the Spanish Lymphoma Group (GELTAMO) (7203 Online Views)

Francisco-Javier Peñalver, Juan-Manuel Sancho, Adolfo de la Fuente, María-Teresa Olave, Alejandro Martín, Carlos Panizo, Elena Pérez, Antonio Salar, Alberto Orfao


Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome (8847 Online Views)

Monique C. Minnema, Eva Kimby, Shirley D’Sa, Luc-Matthieu Fornecker, Stéphanie Poulain, Tom J. Snijders, Efstathios Kastritis, Stéphane Kremer, Aikaterini Fitsiori, Laurence Simon, Frédéric Davi, Michael Lunn, Jorge J. Castillo, Christopher J. Patterson, Magali Le Garff-Tavernier, Myrto Costopoulos, Véronique Leblond, Marie-José Kersten, Meletios A. Dimopoulos, Steven P. Treon


Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation (8289 Online Views)

Inge M. van der Sluis, Lynda M. Vrooman, Rob Pieters, Andre Baruchel, Gabriele Escherich, Nicholas Goulden, Veerle Mondelaers, Jose Sanchez de Toledo, Carmelo Rizzari, Lewis B. Silverman, James A. Whitlock


European Myeloma Network Guidelines for the Management of Multiple Myeloma-related Complications (8426 Online Views)

Evangelos Terpos, Martina Kleber, Monika Engelhardt, Sonja Zweegman, Francesca Gay, Efstathios Kastritis, Niels W.C.J. van de Donk, Benedetto Bruno, Orhan Sezer, Annemiek Broijl, Sara Bringhen, Meral Beksac, Alessandra Larocca, Roman Hajek, Pellegrino Musto, Hans Erik Johnsen, Fortunato Morabito, Heinz Ludwig, Michele Cavo, Hermann Einsele, Pieter Sonneveld, Meletios A. Dimopoulos, Antonio Palumbo


An International MDS/MPN Working Group’s perspective and recommendations on molecular pathogenesis, diagnosis and clinical characterization of myelodysplastic/myeloproliferative neoplasms (5145 Online Views)

Tariq I. Mughal, Nicholas C.P. Cross, Eric Padron, Ramon V. Tiu, Michael Savona, Luca Malcovati, Raoul Tibes, Rami S. Komrokji, Jean-Jacques Kiladjian, Guillermo Garcia-Manero, Attilio Orazi, Ruben Mesa, Jaroslaw P. Maciejewski, Pierre Fenaux, Raphael Itzykson, Ghulam Mufti, Eric Solary, Alan F. List


Consensus recommendations for the diagnosis and management of hemophagocytic lymphohistiocytosis associated with malignancies (2721 Online Views)

Kai Lehmberg, Kim E. Nichols, Jan-Inge Henter, Michael Girschikofsky, Tatiana Greenwood, Michael Jordan, Ashish Kumar, Milen Minkov, Paul La Rosée, Sheila Weitzman


Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia (2178 Online Views)

Charlotte M. Niemeyer, Mignon L. Loh, Annamaria Cseh, Todd Cooper, Christopher C. Dvorak, Rebecca Chan, Blanca Xicoy, Ulrich Germing, Seiji Kojima, Atsushi Manabe, Michael Dworzak, Barbara De Moerloose, Jan Starý, Owen P. Smith, Riccardo Masetti, Albert Catala, Eva Bergstraesser, Marek Ussowicz, Oskana Fabri, André Baruchel, Hélène Cavé, Michel Zwaan, Franco Locatelli, Henrik Hasle, Marry M. van den Heuvel-Eibrink, Christian Flotho, Ayami Yoshimi


Hypersensitivity reactions to intravenous iron: guidance for risk minimization and management (23754 Online Views)

David Rampton, Joergen Folkersen, Steven Fishbane, Michael Hedenus, Stefanie Howaldt, Francesco Locatelli, Shalini Patni, Janos Szebeni, Guenter Weiss


MDM2 promotor polymorphism and disease characteristics in chronic lymphocytic leukemia: results of an individual patient data-based meta-analysis (1403 Online Views)

Axel Benner, Larry Mansouri, Davide Rossi, Aneela Majid, Kerstin Willander, Anton Parker, Gareth Bond, Sarka Pavlova, Holger Nückel, Olaf Merkel, Paolo Ghia, Emili Montserrat, Mohd Arifin Kaderi, Richard Rosenquist, Gianluca Gaidano, Martin J.S. Dyer, Peter Söderkvist, Mats Linderholm, David Oscier, Zuzana Tvaruzkova, Sarka Pospisilova, Ulrich Dührsen, Richard Greil, Hartmut Döhner, Stephan Stilgenbauer, Thorsten Zenz


The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: recommendations from the European Myeloma Network (6223 Online Views)

Niels W.C.J. van de Donk, Antonio Palumbo, Hans Erik Johnsen, Monika Engelhardt, Francesca Gay, Henrik Gregersen, Roman Hajek, Martina Kleber, Heinz Ludwig, Gareth Morgan, Pellegrino Musto, Torben Plesner, Orhan Sezer, Evangelos Terpos, Anders Waage, Sonja Zweegman, Hermann Einsele, Pieter Sonneveld, Henk M. Lokhorst


Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel (9975 Online Views)

Emanuele Angelucci, Susanne Matthes-Martin, Donatella Baronciani, Françoise Bernaudin, Sonia Bonanomi, Maria Domenica Cappellini, Jean-Hugues Dalle, Paolo Di Bartolomeo, Cristina Díaz de Heredia, Roswitha Dickerhoff, Claudio Giardini, Eliane Gluckman, Ayad Achmed Hussein, Naynesh Kamani, Milen Minkov, Franco Locatelli, Vanderson Rocha, Petr Sedlacek, Frans Smiers, Isabelle Thuret, Isaac Yaniv, Marina Cavazzana, Christina Peters


European Myeloma Network recommendations on the evaluation and treatment of newly diagnosed patients with multiple myeloma (4782 Online Views)

Monika Engelhardt, Evangelos Terpos, Martina Kleber, Francesca Gay, Ralph Wäsch, Gareth Morgan, Michele Cavo, Niels van de Donk, Andreas Beilhack, Benedetto Bruno, Hans Erik Johnsen, Roman Hajek, Christoph Driessen, Heinz Ludwig, Meral Beksac, Mario Boccadoro, Christian Straka, Sara Brighen, Martin Gramatzki, Alessandra Larocca, Henk Lokhorst, Valeria Magarotto, Fortunato Morabito, Meletios A. Dimopoulos, Hermann Einsele, Pieter Sonneveld, Antonio Palumbo


Targeted therapy against multi-resistant bacteria in leukemic and hematopoietic stem cell transplant recipients: guidelines of the 4th European Conference on Infections in Leukemia (ECIL-4, 2011) (2999 Online Views)

Diana Averbuch, Catherine Cordonnier, David M. Livermore, Małgorzata Mikulska, Christina Orasch, Claudio Viscoli, Inge C. Gyssens, Winfried V. Kern, Galina Klyasova, Oscar Marchetti, Dan Engelhard, Murat Akova


European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia (12279 Online Views)

Diana Averbuch, Christina Orasch, Catherine Cordonnier, David M. Livermore, Małgorzata Mikulska, Claudio Viscoli, Inge C. Gyssens, Winfried V. Kern, Galina Klyasova, Oscar Marchetti, Dan Engelhard, Murat Akova



Evidence- and consensus-based practice guidelines for the therapy of primary myelodysplastic syndromes. A statement from the Italian Society of Hematology (773 Online Views)

EP Alessandrino, S Amadori, G Barosi, M Cazzola, A Grossi, LN Liberato, F Locatelli, M Marchetti, E Morra, P Rebulla, G Visani, S Tura, Italian Society of Hematology